Tetrazine pentapolyethylene glycol active lipid

NegotiableUpdate on 05/06

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Nature of the Manufacturer: Producers

Product Category

Place of Origin

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Overview

Tetrazine pentapolyethylene glycol active lipid has N-hydroxysuccinimide (NHS) ester that can react with primary amines and tetrazine that can react with trans cyclooctene.

Product Details

Tetrazine pentapolyethylene glycol active lipid

Chinese name: Tetrazine pentapolyethylene glycol active lipid

English name: Tetrazine-PEG5-NHS ester

CAS：1682653-80-0

Chemical formula: C27H36N6O10

Molecular weight: 604.61

3、 Product details:

Appearance: Red amorphous solid or red oily substance

Specifications: 10mg, 25mg, 100mg

Delivery time: Decided based on whether customization is required

Purity: 95%

Purpose: Experimental use, scientific research and development, customizable services

Storage conditions: Dry, away from light, short-term (days to weeks) at 0-4 ° C or long-term (months to years) at -20 ° C.

四嗪-五聚乙二醇-活性脂

Product Introduction:

Tetrazine-PEG5-NHS ester has N-hydroxysuccinimide (NHS) ester that can react with primary amines and tetrazine that can react with trans cyclooctene. Hydrogen substituted tetrazine exhibits kinetics that are typically at least 10 times faster than methyl substituted tetrazine. The hydrophilic polyethylene glycol (PEG) spacer arm significantly improves the water solubility of the reagent.

Tetrazine-PEG5-NHS ester is a PEG derivative containing a tetrazine group and NHS ester. It is one of the responsive tetrazine compounds.

Tetrazine-PEG5 Active Ester is a compound that combines a tetrazine group, five ethylene glycol units (PEG5), and an active lipid group. This molecule has important applications in the fields of chemical biology and biological covalent synthesis, especially for specific labeling and coupling of biomolecules.

chemical structure

Tetrazine: A highly specific alkyne reactant that can undergo rapid and efficient reverse cycloaddition reactions with alkynyl compounds such as diynylethyl.

PEG5 (Polyethylene Glycol, 5 units): A flexible chain segment composed of five ethylene glycol units, which increases the water solubility and biocompatibility of the molecule while reducing non-specific binding and background noise.

Active Ester: Having carboxyl and active groups, it is commonly used in esterification reactions with amino compounds such as amino acids, peptides, or proteins.