Ceramic Anti-Mouse PD-1 Antibody (RMP1-14)

Pottery technique T78269 Anti-Mouse PD-1 Antibody (RMP1-14)

Ceramic Anti-Mouse PD-1 Antibody (RMP1-14)

Product Item Number:T78269

Product Name:Anti-Mouse PD-1 Antibody (RMP1-14)

Product Specifications1mg/5mg/10mg25mg/50mg

Product Introduction:

RMP1-14 is an IgG like immunoglobulin against mouse PD-1 antibody that can block PD-1/PD-L1 signaling.

The specific product parameters are subject to the parameters in the product manual received

Product Description

RMP1-14 is an IgG-like immunoglobulin and anti-Mouse PD-1 antibody that blocks PD-1/PD-L1 signaling.

In vitro activity

Mouse PD1 recombinant protein was used as the antigen, and RPM1-14 was used as the antibody to detect EC50 binding data.

In vivo activity

Subcutaneous injection in miceMC38 (1 × 106) or B16-hCXCR4 (5 × 105). Two weeks later, tumor bearing mice were treated intraperitoneally (ip) with anti-PD-1 [RMP1-14] (5 mg/kg, twice a week, for 2 weeks), Pep R (2 mg/kg, 5 days a week, for 2 weeks), or both drugs. The results showed that combination therapy with Pep R and anti-PD-1 resulted in a 2.67-fold reduction in relative tumor volume (RTV) of MC38 (p=0.038), while the use of anti-PD-1 and Pep R alone did not significantly affect tumor growth [2].

storageLow temperature storage | stored at -80 ° C | transported using blue ice.

Ceramic Anti-Mouse PD-1 Antibody (RMP1-14)

Product ordering information:

T78269 Anti-Mouse PD-1 Antibody (RMP1-14) 1mg/5mg/10mg25mg/50mg

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