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Xi'an Huirui Biotechnology Co., Ltd

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DSPE-PEG-OH, Main characteristics of phospholipid polyethylene glycol hydroxyl group
Date: 2025-04-08Read: 3

Name: DSPE-PEG-OH, Phospholipid Polyethylene Glycol Hydroxyl

Introduction:

DSPE-PEG-OH (Phospholipid Polyethylene Glycol Hydroxyl) is a common surface modified molecule widely used in the biomedical field, especially in drug delivery, molecular imaging, and the development of nano drug carriers. It is composed of distearoyl phosphatidylethanolamine (DSPE) and polyethylene glycol (PEG) chains, and has a hydroxyl (- OH) group at the end of the PEG chain. This molecule combines the advantages of phospholipids and polyethylene glycol, and has many important biomedical applications.

Main features:

  1. Improvement of water solubilityThe PEG moiety endows DSPE-PEG-OH with good water solubility and biocompatibility, allowing it to exist stably in aqueous environments.

  2. Enhance drug deliveryDue to the "invisible effect" of PEG, DSPE-PEG-OH can effectively avoid recognition by the immune system, thereby increasing the circulation time of drugs in the body.

  3. surface modificationThis molecule can be used to modify the surface of nanoparticles, enhance their affinity with cells or other target tissues, while reducing non-specific adsorption.

Application:

  1. Drug delivery systemDSPE-PEG-OH is often used as a surface modifier for carriers such as liposomes and nanoparticles to enhance drug stability and bioavailability. Its PEG chain can effectively shield the nanocarrier, allowing it to stay in the blood for a longer period of time and reducing the chance of being cleared.

  2. Targeted deliveryBy further introducing targeting molecules (such as antibodies or ligands) onto the PEG chain, nanocarriers can be used for targeted drug delivery to specific cells or tissues.

  3. Molecular ImagingDSPE-PEG-OH has also been widely used in molecular imaging, especially in the development of nano contrast agents, which helps to improve the resolution and targeting of images.

Overall, DSPE-PEG-OH has become an important material in biomedical research due to its excellent biocompatibility and tunable chemical structure.

Packaging: Bottled

Origin: Xi'an

Storage: Refrigerated

Status: Solid/Powder/Solution

Specification: 50mg 100mg 250mg 500mg

DSPE-PEG-OH,磷脂聚乙二醇羟基

About Us:

Xi'an Huirui Biotechnology is a high-tech enterprise that integrates research and development, production, and sales of high-quality scientific research reagents. Its main business directions include: synthesis of phospholipids, polymer polyethylene glycol derivatives, block copolymers, paramagnetic/superparamagnetic nanoparticles, nano gold and nano gold rods, near-infrared fluorescent dyes, reactive fluorescent dyes, fluorescently labeled glucan BSA and streptavidin, protein crosslinkers, small molecule PEG derivatives, click chemistry products, dendritic polymers, cyclodextrin derivatives, macrocyclic ligands, fluorescent quantum dots, hyaluronic acid derivatives, graphene or graphene oxide, carbon nanotubes, fullerenes, etc. It also provides various customized product services!

The above information is provided by the editor kx and is only for scientific research purposes!

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