1 Sample description
Test Sample: Powder Particle Sample Introduction: This experiment mainly tests the infrared spectrum of the sampleFenHigh complex samples of thiazide by-productsFenDetect the content of thiazide.

2 Equipment method
Using equipment:iCAN 9Fourier transform infrared spectrometer transmission test method: resolution4cm-1Spectral scanning frequency32 Next time.

Test scenario example



Test results:

Infrared analysis:

2. Sample high complex of phenothiazine by-products


The comparison between high complex of phenothiazine and phenothiazine by-products is as follows: quantitative analysis can be performed based on the peak height of 3340cm-1.

| | Sampling amount (mg) | Corresponding absorbance | Correct absorbance | Phenothiazine content |
| Phenothiazine pure substance | 2.2 | 0.7520 | 0.7520 | 99.97% |
| Phenolthiazide by-products | 2.5 | 0.2613 | 0.2299 | 30.60% |
The use of infrared spectroscopy to detect the content of phenothiazine in high complex by-products of phenothiazine is an effective analytical method based on molecular vibration characteristics. This method achieves accurate determination of the target compound content by capturing the characteristic absorption peaks of phenothiazine molecules in the infrared spectrum region. Although there may be challenges in sample preparation, instrument parameter adjustment, and data processing in practical operations, infrared spectroscopy has shown broad application prospects in the quality control, impurity analysis, and new drug development of phenothiazine drugs due to its non-destructive, rapid response, and high sensitivity characteristics. By continuously optimizing experimental conditions and data processing methods, infrared spectroscopy will provide more reliable technical support for the accurate detection of phenothiazine content in high complex phenothiazine by-products. Friends with relevant application needs can contact us.