Infrared spectroscopy has been widely used in the field of pharmaceutical detection due to its simple operation, accuracy, and speed. Medroxyprogesterone acetate tablets are included in the "Infrared Spectroscopy Collection of Drugs" and are widely used in menstrual disorders, functional uterine bleeding, and endometriosis. Having a significant market share in the pharmaceutical industry，Recently, we conducted an inspection on the powder of medroxyprogesterone acetate.