Caliper IVIS Lumina IIReal time, dynamic, non-invasive observation of biological processes in living animals is achieved through multimodal imaging techniques such as bioluminescence, fluorescence, CT/MRI, etc.

　　Caliper IVIS Lumina IIThe core value of "non-invasive, dynamic, and precise" lies in its advantages over traditional methods of "anatomical sampling+in vitro testing"

1. Non invasive, reducing experimental errors

Data can be obtained without the need to euthanize animals, avoiding "tissue damage caused by anatomical processes" and "errors caused by individual differences in different animals". For example, when studying tumor growth, multiple imaging of the same mouse can be performed to directly observe the true growth process of the tumor in vivo, without the need for indirect inference through "killing multiple mice and weighing the tumor", resulting in more accurate data.

2. Dynamic tracking, capturing real-time processes

Real time monitoring of dynamic changes in animal bodies, such as the distribution process of drugs in the body; The migration trajectory of cells; The development process of the disease.

3. Reduce animal usage and comply with ethical requirements

Traditional methods require the detection of multiple animals corresponding to different time points (such as 10 mice corresponding to 10 time points), while in vivo imaging systems can track the same animal for a long time (one mouse can cover multiple time points), greatly reducing the amount of experimental animals used and meeting the ethical requirements of animal experiments based on the "3R principle".

4. High sensitivity and precise quantification

It can detect "trace signals in the body" (such as optical imaging can detect less than 10 fluorescently labeled cells, and nuclear imaging can detect picomolar level probes), and the signals can be accurately quantified through software, avoiding the subjective errors of traditional "visual observation+manual measurement" and achieving higher data repeatability.

5. Multi dimensional information fusion

Multimodal imaging (such as optical+CT, PET+MRI) can simultaneously obtain "molecular functional information" and "anatomical structure information".