SkyScan2214 CMOS is an advanced nanoscale X-ray 3D imaging device, whose resolution capability represents the advanced level of current laboratory X-ray 3D imaging technology. The image resolution can reach 60nm, and the spatial resolution can reach<500nm. In addition, SkyScan2214 is a device capable of cross scale characterization, suitable for sample sizes ranging from small to tens of microns to large, such as diameter 300mm and height 400mm. Of course, the capability of the device cannot be separated from the strong support of hardware. SkyScan2214 CMOS adopts an open tube transmission radiation source that can achieve a smaller focal size. During use, only the filament needs to be replaced, which not only reduces maintenance costs but also ensures that the radiation source performance is always maintained in a high-efficiency state, thereby ensuring the quality of the output image. In addition, in terms of the traditional advantageous component of the SKyScan2214 device - the detector, the SkyScan2214 CMOS retains the multi detector configuration of the previous generation product (up to 4 can be configured), and has upgraded the hardware to a research grade CMOS detector, which means a larger imaging field of view, faster scanning speed, and better image quality for users.