Sanqi is the dried root and rhizome of the plant Sanqi in the Araliaceae family, which has the effects of dispersing blood stasis, stopping bleeding, reducing swelling, and relieving pain. The main active ingredients in Sanqi are Sanqi saponinsR1GinsenosidesRg1GinsenosidesRb1The effective determination of its content is of great significance for the quality control of Panax notoginseng medicinal materials. This experiment is conducted according to2020The Chinese Pharmacopoeia requires the use ofHPLCThe law,HOLOWAThe core-shell chromatography column achieved efficient separation of several saponins in Panax notoginseng medicinal materials.