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Solution for Tongwei 2020 New Pharmacopoeia: HPLC-ELSD Detection of Platycodon Saponin D in Platycodon grandiflorus
Date: 2024-03-06Read: 0

Platycodon grandiflorus is the dried root of Platycodon grandiflorus, a plant in the family Platycodon grandiflorus. It has the effects of promoting lung function and throat function, among which Platycodon grandiflorus saponin D is its main medicinal and effective ingredientIngredients.Platycodin DUV absorption is weak and conventional liquid chromatography UV detectors should not be used for detection, 《The Chinese PharmacopoeiaIt is also stipulated to use a universal detector ELSD for the detection of active ingredients in Platycodon grandiflorum.Compared to the 2015 edition of the Chinese Pharmacopoeia,2020 edition of the Chinese PharmacopoeiaThe pre-treatment method for the Platycodon grandiflorum sample has also been adjusted. If the original method is used for separation and analysis, some problems may be encountered.Therefore,In order to facilitate users to analyze and detect the sample according to the 2020 edition of the Chinese Pharmacopoeia, Shanghai Tong Micro Analysis TechnologyLimited company, in accordance with the requirements of the 2020 edition of the Chinese Pharmacopoeia, has used HPLC-ELSD to achieve the separation and detection of saponins D in Platycodon grandiflorum, which can meet the daily quality control requirements of Platycodon grandiflorum.