What factors affect the efficiency of rotary evaporator distillation in daily use?

1.Heating pot temperature

The higher the temperature of the heating pot, the faster the distillation effect of the solvent. However, considering the thermal sensitivity of the target component and the safety of the operation, the most commonly used temperature is60℃. Furthermore80°CAbove all, using silicone oil as a medium will bring cleaning problems, and it is generally recommended to lower the vacuum value to achieve faster distillation efficiency.

2.Temperature of cooling medium

To ensure the distillation efficiency of *, it is generally recommended to maintain the cooling medium at the same temperature as the heating pot40°CThe temperature difference is adjusted to facilitate rapid condensation of hot steam and reduce the impact of steam on the system vacuum.

3.Vacuum value of the system

Vacuum pump and vacuum controller: The lower the limit of the vacuum pump, the lower the vacuum value of the system. During distillation, it is necessary to set a reasonable vacuum value through a vacuum controller to ensure distillation efficiency and avoid boiling. Sealing ring: As a key sealing component for connecting evaporator and condenser tubes, its wear resistance and corrosion resistance are crucial. The materials commonly used as sealing rings are:PTFEAnd rubber, obviouslyPTFEThe wear resistance and corrosion resistance will be better.