1、 Technical features

The PCRmax PCR instrument adopts the latest thermal cycling technology and has the following significant features:

1. Precise temperature control system: Using advanced Peltier elements and PID control algorithm, it can achieve temperature control accuracy of ± 0.1 ℃, ensuring temperature accuracy in each cycle stage, which is crucial for the reliability of medical testing results.

2. Rapid temperature rise and fall rate: The maximum temperature rise and fall rate can reach 6 ℃/s, greatly reducing detection time and enabling routine PCR testing to be completed within 30 minutes, greatly improving clinical testing efficiency.

3. Multi detection capability: Supports up to 6 channels of fluorescence detection, which can simultaneously detect multiple pathogens or genetic markers, meeting complex medical diagnostic needs.

4. Intelligent software system: equipped with an intuitive operating interface and powerful data analysis software, simplifying the operation process and reducing human errors.

2、 Performance in Medical Sample Testing

1. Sensitivity and specificity

It exhibits high sensitivity in medical sample detection and can detect nucleic acid molecules as low as 1-10 copies/μ L. In multiple clinical validation studies, its detection sensitivity for various pathogens (including viruses, bacteria, fungi, etc.) has reached over 99%, and its specificity has exceeded 98%, significantly better than traditional detection methods.

2. Repeatability and consistency

The instrument adopts a uniform hot tank design to ensure that the temperature difference between each hole of the 96 well plate is less than 0.3 ℃, and the coefficient of variation (CV) between holes is usually less than 2%, ensuring a high degree of consistency in batch sample detection results, which is particularly important for large-scale screening and epidemiological monitoring.

3. Anti interference capability

The specially optimized optical system can effectively eliminate the influence of common interfering substances (such as hemoglobin, heparin, etc.) in the sample, ensuring the accuracy of complex clinical sample detection (such as whole blood, sputum, tissue, etc.).

3、 Clinical application advantages

1. Diagnosis of infectious diseases

In the detection of COVID-19, influenza virus, HIV, HBV/HCV and other pathogens, PCRmax PCR instrument shows the characteristics of fast and accurate. Especially during the COVID-19 epidemic, its high-throughput version (384 holes) provided reliable technical support for large-scale screening.

2. Genetic disease screening and prenatal diagnosis

The high sensitivity of the instrument enables accurate detection of gene mutations in trace amounts of fetal DNA, providing a reliable tool for non-invasive prenatal diagnosis of chromosomal abnormalities such as Down syndrome.

3. Molecular diagnosis of tumors

In the fields of tumor related gene mutation detection and circulating tumor DNA analysis, its multi-channel detection capability can achieve synchronous analysis of multiple sites, providing precise molecular basis for personalized medicine.

4. Pharmacogenomics

The instrument performs excellently in detecting genetic polymorphisms of drug metabolizing enzymes such as CYP450, providing important references for rational clinical drug use.

4、 Convenience and safety of operation

The PCR instrument design fully considers the actual needs of medical laboratories:

1. High degree of automation: pre-set commonly used detection programs, support custom protocol storage, simplify operation processes.

2. Anti pollution design: equipped with an anti aerosol pollution system and UV disinfection function to reduce the risk of cross contamination.

3. Comprehensive data management: Supports LIS system integration and meets the requirements of medical laboratory information management.

4. Easy maintenance: Modular design makes daily maintenance and troubleshooting more convenient.