Fully automatic transdermal diffusion apparatusThrough automation control and high-precision design, significant advantages have been demonstrated in fields such as drug development, cosmetics testing, and medical device evaluation.

　　Fully automatic transdermal diffusion apparatusDetailed analysis of its technological advantages:

High precision parameter control

Temperature stability: Using dry heating blocks or circulating water bath systems, the temperature control accuracy is ≤ 0.2 ℃, which can accurately simulate the temperature of human skin (such as 32 ℃), avoiding temperature fluctuations that affect the penetration rate of substances.

Stirring and flow rate control: By using magnetic stirring or micro pump systems, ensure uniform mixing of the receiving medium (such as physiological saline), reduce local concentration differences, and improve experimental reproducibility.

Sampling accuracy: The high-precision injection pump achieves timed and quantitative sampling (error ≤ 0.08ml), supports 12 channel independent operation, and meets the requirements of high-throughput screening.

Fully automated and intelligent

Preset program operation: Users can set experimental parameters (such as temperature, sampling interval, stirring speed) through touch screen or software, and the equipment automatically completes the entire process of sample loading, sampling, and data recording, reducing human operation errors.

Intelligent data analysis: The built-in software can calculate key indicators such as transdermal rate, steady-state permeation rate, and cumulative transmittance per unit area in real time, and generate visual reports. It supports data docking with detection equipment such as HPLC and UV Vis.

Audit tracking function: Compliant with GLP/GMP standards, records all operation logs and parameter changes to ensure data traceability.

Multi channel and modular design

High throughput experiment: Supports synchronous operation of 6-12 independent diffusion pools, for example, PermeGear H series base can be expanded to 9 channels, significantly improving experimental efficiency.

Modular extension: Users can add online analysis modules (such as HPLC connections), multi-channel sampling arms, or temperature control extension units according to their needs, flexibly adapting to different experimental scenarios.

Material compatibility and simulation authenticity

Diversity of skin models: compatible with silicone film, polyurethane film, biological tissues (such as ex vivo pig skin), and 3D skin models, it can simulate the permeation characteristics of different skin types (such as normal skin and thickened stratum corneum skin).

Fluid dynamics optimization: Horizontal diffusion tanks (such as Valia Chien tanks) are designed to reduce bubble interference, while vertical tanks (such as Franz tanks) are easy to operate and meet the testing needs of different substances (such as creams, patches, microneedles).