The Nikon microscope series is designed specifically for biological science research, integrating cutting-edge technologies and achieving remarkable results in fields such as live cell imaging, cell biology, and drug development.
Its core technology lies in the advanced CFI60 ® Optical system, supporting multiple imaging techniques such as TIRF, confocal, fluorescence imaging, etc. Taking TIRF imaging as an example, combined with a 1.49 high numerical aperture objective lens and an external phase difference unit design, ultra-high resolution images can be obtained, clearly showing the subtle structure of the cell surface. It is crucial in studying topics such as intercellular signal transduction and membrane protein distribution. Its excellent focusing system (PFS) can be regarded as a major highlight, which can correct focus drift in real time. In long-term observation of live cells, even if affected by factors such as temperature changes and sample movement, it can ensure focus stability and reduce the impact of phototoxicity on cells, allowing researchers to obtain continuous and stable data on cell dynamic changes.
The microscope adopts ergonomic design, reducing the height of the stage by about 30%, optimizing operational comfort and sample visibility, and reducing the burden of long-term operation for experimental personnel. Some models are equipped with a 25mm wide field of view optical system, LED lighting, and compound eye lens technology, which are compatible with large format CMOS cameras, greatly improving data throughput and suitable for large-scale experiments such as high-throughput drug screening. In addition, the Nikon microscope covers various observation modes such as Nomarski differential interferometry and dark field, and is equipped with powerful NIS Elements imaging analysis software. From basic manual operation to complex fully automatic confocal imaging, it can meet the diverse needs of researchers and provide strong technical support for solving life science problems.