Asymmetric flow field flowmeterIt is a separation analysis technology based on fluid mechanics principles, and its core innovation lies in:
Hollow flat separation channel: replaces the fixed phase of traditional chromatography columns, achieves non fixed phase separation through laminar flow characteristics, and avoids sample adsorption or shear force damage.
Vertical field force effect: Apply alternating electric or flow field force in the vertical direction of the channel, causing the sample particles to focus on the bottom wall of the channel due to differences in diffusion coefficients.
Reverse diffusion separation: Utilizing the inverse relationship between particle size and diffusion rate to achieve continuous separation of nanometer to micrometer sized particles. For example, small particles diffuse quickly and are carried out by channel flow; Large particles diffuse slowly and migrate along the channel under the push of cross flow.
Technical advantages:
No fixed phase design: eliminates sample residue and column efficiency attenuation issues, extending instrument lifespan.
Ultra wide separation range: covering 1 nm to 100 μ m particle size and 500 Da to 10 ¹ ² Da molecular weight, which is far superior to traditional gel permeation chromatography (GPC).
Sample integrity preservation: Mild separation conditions to avoid polymer chain breakage or particle aggregation, suitable for analysis of biomolecules and nanomaterials.
This device can be used to evaluate the size distribution, surface modification, and aggregation mechanism of nanoparticles, and assist in the research and quality control of nanomaterials. Helps to study the stability and additive distribution of emulsions and lipid particles, ensuring product safety and compliance.
Asymmetric flow field flowmeterWith its non fixed phase separation, ultra wide detection range, and multi domain adaptability, it is moving from scientific research laboratories to industrial production lines. With the breakthrough of automation and multi field coupling technology, this device is expected to become a "versatile" platform for analyzing complex fluid samples, providing deeper insights into material structures for nanotechnology, biomedicine, and environmental science.