Traditional small molecule and large molecule drugs are often constrained by their own molecular structures during the research and development process, making them difficult to develop into drugs; Cannot be achieved due to the constraint that the target itself cannot be targetedMedicine. RNA (ribonucleic acid) is an important bridge connecting genes and proteins, so nucleic acid drugs are not only not restricted by their own structure, but can also break the "difficult to form drugs" barrier; It can also significantly expand the target range and break the "non pharmacological" rule; In addition, compared to traditional drugs, its efficacy is more powerful and long-lasting, which is expected to overcome the problems of "insufficient efficacy" of existing therapies. At present, mRNA vaccines, small interfering RNA (siRNA), and antisense oligonucleotides (ASO) are the main forms of nucleic acid drug development in clinical practice. With the innovation of gene sequencing, chemical modification, and delivery systems, nucleic acid drugs are about to enter a harvest period and are expected to become a new generation of iterative treatment solutions.However, currently, the main issues facing the development of nucleic acid drugs (drug stability, targeting, and safety) have not been resolved, and there is an urgent need to develop new generation technologies and rapidly promote their industrialization process. At present, the directions of technological breakthroughs include sequence design technology, structural modification technology, delivery system technology, etc.

2024 Nucleic Acid Drug and mRNA Vaccine Industry Summitwill beHeld in Shanghai on March 28-29At that time, more than 50 experts and experts in the field of nucleic acid drugs will be invited to share new technological breakthroughs and insightsThe progress of nucleic acid drug research and development further promotes the industrialization of nucleic acid. Ruixin Intelligent Manufacturing, as an exhibitor, has been invited to participate in this grand event, and we sincerely invite everyone to join us!