Guangzhou Yuexiu District Center for Disease Control and PreventionIt is the Guangzhou Regional Special Inspection Center for Emerging Infectious Diseases and Foodborne Diseases, with laboratory capabilities reachingNational A-class levelCurrently, it is one of the most important monitoring institutions in Guangzhou for service capacity and response to major public health emergencies.

Xiaorui had the privilege of interviewing Xie Cheng'en, the director of the Physical and Chemical Laboratory Department of Yuexiu CDC, to discuss Xie's ideal and reality of an automated pre-processing laboratory.

"In the grass-roots work, the CDC has many special tasks and insufficient personnel. Especially since the COVID-19, everyone has been involved in the prevention and control work, and the detection personnel have double responsibilities. The laboratory has supplemented pre-treatment equipment for this purpose. Our pre-treatment work has shortened the time by 1/4, and the amount of sample pre-treatment has also increased by 30%.

The purpose of purchasing automated pre-processing equipment in the laboratory is to expand service capabilities and provide technical support for foodborne disease monitoringThat's right

Firstly, it is manually operatedLarge errorThe operator'sThe workload is also heavySecondly, in verifying the dataTraceabilityIn terms of complexity, it is difficult to reproduce all the original records of the pre-processing process; In addition, during the operation, the inspectors are exposed to high concentrations of toxic reagents, which can cause harm to the human bodyHealthIt also causes harm.

In 2015, we purchased the fully automatic solid-phase extraction instrument 02HT from Ruike Group for the first time in food safety risk monitoring. With the application of automated equipment, our laboratory has expanded the sample preparation processSimultaneous development of multiple types of foodThe ability,In daily testing,Our pre-processing work has been reduced by 1/4 of the time, and the amount of sample pre-processing has also increased by 30%.

In addition, our quality control level has also been improved, which helps the laboratory ensure the sensitivity of qualitative and quantitative testing, and has a positive impact on the detection resultsReproducibility and accuracysexI also received help. In grass-roots work, the CDC has many special tasks and insufficient staff, especially since the COVID-19, everyone has been involved in prevention and control,Testing personnel have dual responsibilities. The laboratory has added equipment such as fully automatic solid-phase extraction instrument, fully automatic homogenizer, multifunctional sample preparation workstation, automatic calibration instrument, fully automatic nitrogen blowing concentrator, etc. for this purpose.The purpose of purchasing automated pre-processing equipment in the laboratory is to expand service capabilities and provide technical support for foodborne disease monitoring.

In 2016, during our risk monitoring of veterinary drug residues in Guangzhou, we suddenly discovered that the concentration of chloramphenicol residue in the detection of flower beetle was very high, which was unexpected. At that time, we were very worried that the detection process of this high concentration substance would cause residue and cross contamination of the sample?In response to this issue, Ruike's application engineers promptly optimized our entire flushing processWith their help, we optimized the flushing of key components such as the entire sample pipeline, plunger rod, and injection pump. Our specialized testing was successfully completed,After the review by the municipal CDC, the result is very satisfactory, providing strong assistance for the data monitoring of that year.

We jointly build a laboratory for automation applications with Ruike GroupFor our future method development and talent cultivation, it will play a very helpful role. We will also promote and apply the concept of automation laboratory.

The laboratory pre-processing is developing towards higher efficiency, convenience, less sample usage, and higher data accuracy. It has gradually become a consensus on how to use automated pre-processing to replace manual operation. The ideal way to solve the laboratory dilemma is to modularize and automate the process, preferably with flexible combinations of modules according to customer needs,We will aim to build modern laboratories and jointly promote the application and practice of these automated equipment.