Reactive System Screening InstrumentIt is an advanced experimental equipment that integrates automation control, real-time monitoring, and data analysis. It is mainly used for rapid screening and optimization of chemical reaction systems, and plays an important role in new material research and development, drug synthesis, environmental protection, and other fields. This device provides researchers with a wealth of valuable data by precisely controlling reaction conditions such as temperature, pressure, pH value, stirring speed, and real-time monitoring of key parameters during the reaction process such as reaction rate, conversion rate, product distribution, changes in substance concentration, acidity and alkalinity, and gas generation and consumption. Its core components include the reaction module, control system, and analysis system: the reaction module is usually composed of multiple independent reactors, which can simulate different reaction environments; The control system ensures the accuracy and repeatability of the experiment; The analysis system monitors the reaction process in real time through sensors and detectors, and transmits the data to the computer for processing and analysis.
Reactive System Screening InstrumentAs a key equipment in chemistry, materials science, and drug development, its design integrates multiple precision modules to achieve precise control, real-time monitoring, and efficient screening of reaction conditions. The following is a detailed introduction to its core components:
1. Reaction module
The reaction module is the core execution unit of the screening instrument, responsible for carrying the reaction system and achieving conditional control. Its key features include:
Multi channel independent control: supports simultaneous operation of multiple parallel reactions (such as 8 groups or more), and each channel can independently set parameters such as temperature, pressure, stirring speed, etc. to ensure consistency and comparability of experimental conditions.
Material and volume diversity: Reaction vessels are usually made of corrosion-resistant, high-temperature and high-pressure resistant materials (such as stainless steel, Hastelloy or glass), with a volume range from trace amounts (such as 16mL) to pilot scale (such as 400mL), to meet the needs of different research stages.
Sealing and safety design: equipped with high-pressure sealing structure and safety valve to prevent leakage or explosion caused by uncontrolled reaction. Some systems also integrate pressure sensors and emergency pressure relief devices.
2. Temperature control system
Temperature is a key parameter that affects reaction rate and selectivity. The screening instrument achieves precise temperature control through the following components:
Heating/cooling unit: using electric heating, oil bath or semiconductor cooling technology, covering a wide temperature range (such as -80 ℃ to 300 ℃), meeting the needs of low-temperature crystallization or high-temperature polymerization.
Temperature sensor: High precision thermocouple or RTD sensor monitors the reaction temperature in real time, feeds back to the control system to form a closed-loop regulation, and the accuracy can reach ± 0.1 ℃.
Local heating technology: Some systems (such as photocatalytic reactors) are equipped with local heating modules, which can accurately control temperature in specific areas of the reaction vessel and reduce the impact of thermal gradients.
3. Pressure control system
High pressure reactions (such as hydrogenation and supercritical fluid reactions) require strict pressure management, and the main components include:
Pressure source: Gas cylinders or high-pressure pumps provide the required pressure for the reaction, typically ranging from 0-20MPa, and some systems support inert gas (such as N ₂, Ar) protection.
Pressure sensor and regulating valve: Real time monitoring of pressure changes, maintaining the set value through a proportional regulating valve to ensure that the reaction proceeds under constant pressure conditions.
Safety protection: Equipped with rupture discs or safety valves, which automatically release pressure when the pressure exceeds a threshold to prevent equipment damage or personnel injury.
4. Mixing and Mixing System
Uniform mixing is the key to successful reaction, and the system provides multiple stirring methods:
Magnetic stirring: suitable for low viscosity systems, driven by an external magnet to create an internal stirrer without mechanical seals, reducing the risk of contamination.
Top mounted mechanical stirring: used for reactions involving high viscosity or solids, equipped with a variable frequency motor and adjustable stirring speed (such as 50-1500rpm).
Special mixing design: such as turbine type and anchor type mixing blades, optimized for specific reaction systems (such as suspension polymerization) to improve mixing efficiency.
5. Injection and feeding system
Realize precise addition of reactants and sample collection:
Automatic sampler: liquid or gas reactants are added to the reaction vessel according to a preset program through a pump or syringe, supporting gradient feeding or pulse feeding.
Sample collection valve: Regularly extract samples during the reaction process for online analysis or offline detection. Some systems are equipped with low-temperature cooling devices to prevent sample degradation.
Solid feeder: For solid catalysts or reagents, a vibrating disc or screw conveyor is used to achieve quantitative addition.
6. Monitoring and detection system
Real time acquisition of reaction process data, the main components include:
Sensor array: integrates pH meter, conductivity meter, dissolved oxygen sensor, etc., to monitor key parameters of the reaction system.
Spectral detection module: such as UV Vis, FTIR, or Raman spectroscopy probes, directly inserted into the reaction vessel for in-situ analysis, tracking reactant consumption and product generation.
Gas analysis unit: Analyze gas products online through mass spectrometry (MS) or gas chromatography (GC) to calculate reaction conversion rate or selectivity.
7. Light source system
Photocatalysis or photochemical reactions require dedicated light sources:
LED light source: Provides monochromatic light or simulated solar spectrum, with a wavelength range covering ultraviolet to near-infrared (such as 200-1000nm), and adjustable light intensity.
Fiber optic light guiding system: evenly guide light into the reaction vessel to avoid light attenuation or hotspots, and some systems support multi wavelength synchronous irradiation.
Light intensity monitoring: Equipped with an optical power meter for real-time calibration of light intensity to ensure experimental reproducibility.
8. Control System and Software
Integrated Control and Data Analysis Platform:
Central control unit: Set reaction parameters through touch screen or upper computer software, monitor real-time data, support remote operation and fault diagnosis.
Data collection and processing: Automatically record parameters such as temperature, pressure, stirring speed, etc., generate trend charts or reports, support data export and third-party software analysis.
Simulation and optimization functions: Some software has built-in reaction kinetics models that can predict reaction pathways or optimize process conditions, accelerating the research and development process.
9. Safety and Protection System
Ensure experimental safety:
Emergency stop button: One click to cut off all energy supply and quickly terminate the reaction.
Gas leak detection: equipped with combustible or toxic gas sensors, triggering alarms and activating ventilation systems.
Explosion proof design: The reaction vessel and electrical components adopt explosion-proof structure, which complies with international safety standards (such as ATEX, CE certification).