The fully automatic sample concentrator achieves efficient, accurate, and safe concentration of samples through integrated heating and evaporation, vacuum pressure reduction, intelligent control, and safety protection technologies. Its working principle and core technologies are as follows:

1、 Working principle

Heating and evaporation: The instrument is equipped with a precision temperature control module, which directly heats the sample holder or water bath circulation system to evaporate the solvent at a controllable temperature (room temperature to 95 ℃± 0.5 ℃). For example, water bath heating combined with nitrogen purging can accelerate solvent evaporation while avoiding local overheating that may cause sample denaturation.

Vacuum pressure reduction: Some models use vacuum pumps to reduce system pressure, significantly lowering the boiling point of solvents and achieving low-temperature evaporation. For example, in a vacuum state, the boiling point of water can drop from 100 ℃ to below 40 ℃, thereby protecting thermosensitive substances such as proteins and nucleic acids from high temperature damage.

Intelligent control: The instrument automatically identifies the concentration endpoint (such as 1.0ml, 0.5ml, or near dry 0.1ml) through optical sensors or liquid level sensors, and supports ten level sensitivity adjustment to adapt to solvents with different translucency. After the endpoint is determined, the system automatically stops blowing or heating to avoid loss of the target object.

2、 Core Technology

Sealed blowing and exhaust gas treatment: The sealed chamber is designed with a strong exhaust device to collect and discharge organic solvent vapors in a directional manner, preventing the spread of toxic volatile substances and protecting the health of operators.

Dynamic temperature equalization and cross contamination prevention: The dynamic water bath temperature equalization system maintains uniform water temperature through a circulating pump, ensuring that the temperature deviation of each well position is ≤ 0.5 ℃, and ensuring the parallelism of sample concentration; 16 channel independent vacuum pipeline design to avoid cross contamination between samples.

Gradient negative pressure and anti boiling: adopting a digital vacuum control mode, supporting gradient negative pressure adjustment (such as rapid evaporation of a large amount of solvent in the initial stage, and reducing pressure in the later stage to prevent boiling); The circular shaking function increases the evaporation area, promotes the mixing of the sample solution, and further suppresses the phenomenon of boiling.