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Brooke supports advanced life science and green technology research in the UK
Date: 2023-07-28Read: 0

At the 2023 European Rome conference held in Scotland, Brooke showcased the latest innovations in magnetic resonance technology for life sciences and materials science research. Brooke's contribution to British science will be made through two recently ordered machines from the University of Warwick and the University of Birmingham1.2 GHz Advanced™ The nuclear magnetic resonance (NMR) spectrometer has been further enhanced. This significant investment in scientific infrastructure will enable groundbreaking research on the material properties of energy storage and biofuels, as well as the structures and interactions of proteins, nucleic acids, carbohydrates, lipids, and metabolites in cellular and pathological biology research and drug discovery.

面向与供应商无关的软件的SciY产品平台(图示:美国商业资讯)

SciY product platform for software unrelated to suppliers

The University of Warwick and the University of Birmingham have both used Brooke 1.0 GHz NMR spectrometers, with an additional 1.2 GHz Avance ™ The system will drive this core UK nuclear magnetic resonance research infrastructure with sensitivity and resolution, enabling scientists to delve deeper into the complexity of materials and biomolecule systems.

Brooke also showcased a new modelAscend Evo 400The MHz NMR magnet sets new standards for ease of operation and cost of ownership, reducing liquid helium retention time by one year, lowering the frequency of helium injection, and simplifying laboratory operations. This new type of magnet further improves field uniformity by adopting a new low-temperature homogenization technology originally developed for ultra-high field magnets, making sample homogenization and operation easier.

Brooke is committed to providing solutions that reduce helium consumption, such as a new type used to collect helium evaporation from magnetsHelioSmart-RSystem.HelioSmart-RThe recycling solution has been successfully installed in pharmaceutical laboratories (Merck in Darmstadt, Germany) and academic laboratories (University of South Carolina, USA), and Brooke expects to install a large number of other equipment by 2023. Used for liquefactionNew HelioSmart-LThe solution can collect and liquefy helium gas from nuclear magnetic resonance magnets through evaporation, with a recovery rate of over 95%.HelioSmart-LCollect steady-state helium gas evaporation during operation and refueling, then purify and liquefy helium gas - creating a closed loop to improve sustainability.

Brooke has promoted cooperation with Swiss Federal Institute of Technology Zurich (ETHZ) in accelerating protein structure determination through AI. The core of cooperation isNMRtistThis is a cloud computing service that uses deep learning based methods to automate protein nuclear magnetic resonance spectroscopy analysis.

Professor Roland Riek, head of the Biological Nuclear Magnetic Resonance (NMR) team at the Department of Chemistry and Applied Biosciences at ETH Zurich, commented, "Determining protein structure through NMR is a very time-consuming process that requires a lot of manual intervention. Our goal is to use deep learning and artificial intelligence to make it faster and more automated, while still obtaining accurate results.

NMRtistThe results obtained from cloud based platforms, such as resonance allocation, will be seamlessly integrated into more complex workflows in the future to solve various research problems. The collaboration between Brooke and ETH Zurich marks an important step in advancing protein structure determination. With AI driven automation at its core, this collaborative relationship will continue to provide researchers with faster access to accurate results for many categories of proteins, while saving time and costs in the process.

Brooke recently launchedSciYThe platform provides advanced and universal software solutions for data analysis and management, digitalization of research laboratories and biological production quality control, and automation of scientific workflows. By integrating high-performance laboratory software solutions,SciYThe platform provides a wide range of vendor agnostic software and automation solutions for the digital transformation of the life sciences and biopharmaceutical industries. The launch of SciY is led by Brooke's Integrated Data Solutions department, in collaboration with software and biopharmaceutical automation companies Mestrelab Research, Arxspan, Optimal Industrial Technologies, ZONTAL, and Optimal Industrial Automation. With innovative modular software solutions,SciYThe platform simplifies data collection and interpretation, maximizing the value of data in biopharmaceutical research, development, and manufacturing.

Dr. Falko Busse, President of Brook BioSpin Group, summarized: "We are delighted to support the progress of science and drug discovery research in the UK through Brook's innovation. We believe that investment in life and materials science research infrastructure in the UK is crucial for the development of science, drug discovery, and green technology economy, and we are proud to support these visionary efforts. Our latest advances in magnetic resonance instruments and software, now enhanced by artificial intelligence, will provide our clients with greater scientific research capabilities and productivity.


About Brooke Company

Brooke enables scientists to make breakthrough discoveries and develop new applications, thereby improving the quality of human life. Brooke's high-performance scientific instruments and high-value analytical and diagnostic solutions enable scientists to explore life and materials at the molecular, cellular, and microscopic levels. Through close collaboration with clients, Bruker achieves innovation, productivity improvement, and customer success in life science molecular and cell biology research, applications and pharmaceutical applications, microscopy and nanoanalysis, and industrial applications. Brooke provides differentiated, high-value life science and diagnostic systems and solutions in preclinical imaging, clinical phenotype omics research, proteomics and multi omics, spatial and single-cell biology, functional structure and condensed matter biology, as well as clinical microbiology and molecular diagnostics