Extended ultrasonic disruptor is a multifunctional laboratory equipment based on ultrasonic cavitation effect. It generates the expansion and rupture of small bubbles in liquid through high-frequency mechanical vibration, releasing huge energy to form shock waves and shear forces, achieving efficient fragmentation and dispersion of cells, tissues, and particles. Its core functions and application scenarios are as follows:
1、 Core functions
Cell fragmentation and tissue lysis
Applicable samples: biological samples such as animal and plant cells, bacteria, fungi, virus spores, etc.
Advantages: Non contact processing avoids mechanical friction contamination, especially suitable for sterile samples (such as vaccine preparation); The distribution of cavitation is uniform, the degree of fragmentation is consistent, and the coefficient of variation (CV) within/between batches is less than 5%, which is superior to traditional mechanical grinding methods (CV>15%).
Typical applications: Extracting intracellular products (such as enzymes, plasmid DNA, recombinant proteins) for downstream experiments such as Western Blot and PCR; Virus inactivation research; Homogenization of tissues (such as liver and tumor samples) is used for RNA/DNA extraction.
Dispersion and emulsification of nanomaterials
Function: Decompose and agglomerate metal/oxide nanoparticles (such as Au, TiO ₂), disperse two-dimensional materials such as graphene and carbon nanotubes, prevent agglomeration and improve performance.
Emulsification capacity: prepare micron/nanometer lotion (such as liposomes and microcapsules) to support the development of drug delivery systems.
Advantages: Compared to traditional emulsification methods, ultrasonic emulsification has a narrower particle size distribution and higher stability.
Accelerate chemical reactions and extraction
Catalytic enhancement: promoting the mixing of reactants through cavitation effect, accelerating chemical synthesis (such as the preparation of organic metal framework materials).
Extraction efficiency: dispersing organic pollutants (such as polycyclic aromatic hydrocarbons) in soil or sediment to improve detection sensitivity; Accelerate the dissolution of effective ingredients in Chinese herbal medicine and improve extraction efficiency.
Multi functional sample processing
Capacity adaptation: Supports sample processing from trace amounts (0.1mL) to pilot scale (5L), covering various containers such as centrifuge tubes, beakers, reaction vessels, etc.
Temperature control: Optional cooling circulation system (such as water bath jacket or Peltier refrigeration) can be equipped to maintain the sample temperature at 4-10 ℃ and prevent the deactivation of thermosensitive components.
2、 Technical features
High-frequency cavitation effect
Frequency range: 20-40kHz, low frequency (such as 20kHz) provides high energy, suitable for hard tissue fragmentation; High frequency (such as 40kHz) is used for fine emulsification.
Impact strength: The shock wave released when the cavitation bubble ruptures can reach 1000MPa, efficiently breaking cell walls or nanoparticles.
intelligent control system
Parameter adjustment: Power range 50W-2000W, finely adjustable (± 1% accuracy), suitable for fragile cells (such as mammalian cells) or stubborn samples (such as bacterial spores).
Pulse mode: supports intermittent operation (such as working for 2 seconds/pausing for 1 second) to avoid prolonged ultrasonic heat generation and damage to temperature sensitive samples.
Program storage: Up to 20 sets of operation programs can be created and stored, supporting repeated experimental operations to improve work efficiency.
Security protection design
Soundproof protective cover: reduces noise by<70dB, prevents aerosol diffusion, and protects the health of operators.
Overload protection: Real time monitoring of power, temperature, and working time, automatic shutdown when exceeding limits, to avoid equipment damage.
Probe compatibility: Equipped with titanium alloy amplitude rods of different diameters (2-25mm), corrosion-resistant and fatigue resistant, with a lifespan of up to thousands of hours.
3、 Application scenarios
Biomedical field
Cell lysis: Extraction of recombinant proteins and isolation of mitochondria/chloroplasts.
Vaccine development: using ultrasound to break down the virus envelope for virus inactivation or pathogen research.
Liquid biopsy: Processing blood samples to release free DNA (such as tumor marker detection).
Materials Science Field
Preparation of nanomaterials: dispersing quantum dots and metal nanoparticles to enhance the catalytic performance of materials.
Lithium battery electrode material: uniformly dispersing active materials to improve battery energy density.
Green chemistry: Ultrasonic assisted catalytic reactions reduce solvent usage and energy consumption.
Environmental engineering field
Pollutant detection: Disperse microplastic particles in soil or water to improve extraction efficiency.
Microbial analysis: Quickly break down pathogenic bacteria (such as Escherichia coli) in food/water samples and release nucleic acids for PCR detection.
Food industry sector
Emulsification homogenization: prepare stable lotion (such as beverage and sauce) to improve the taste of products.
Additive extraction: Extracting natural ingredients such as pigments and fragrances from plants.