Using iQuad 2300 kinetic energy discrimination mode (KED mode) for detection significantly reduces the interference of multi atomic ions in the matrix. In response to the high content of nutrients such as K and Na coexisting with trace heavy metals in dairy products, the electronic dilution technology of iQuad 2300 can be used to set differentiated dilution parameters for target elements, achieving synchronous determination of nutrient and heavy metal content in a single injection.