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Hangzhou Qikun Technology Co., Ltd

  • E-mail

    qikun@hzqikun.com

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    13858055033

  • Address

    No. 2 Houxi Road, Fengchuan Street, Tonglu, Hangzhou City, Zhejiang Province

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Implementing integrated control of isolator host PLC for sterile isolator in hard cabin
Date: 2017-10-17Read: 0

  Hard cabin sterile isolatorRealize integrated control of isolator host PLC
  
  Hard cabin sterile isolatorfeature
  
1. The material of the sterile isolator for the hard cabin is 316L stainless steel plate with a thickness of 2-3mm, fully welded and polished as a whole. The interior of the cabin has rounded corners and transitions. The door is made of 15mm thick white tempered glass, which has good transparency and mechanical strength. It can be opened at a high angle using gas springs and does not affect the cleaning operation inside the cabin.
  
2. The air filtration and inlet/outlet mechanism of the sterile isolator in the hard cabin is mainly composed of low-noise fan H14 level filter, uniform flow membrane and return air (exhaust) filter, electric butterfly valve and pipeline, ensuring that the interior of the isolator meets dynamic cleanliness standards, and that microorganisms and particles outside the cabin will not be brought into the isolator during the air exchange process inside and outside the cabin.
  
3. By using a programmable logic controller (PLC) and a frequency converter to automatically control the inlet and outlet fans of the isolator, a certain pressure difference is ensured within the cabin to maintain a sterile state. Conventional product production uses a positive pressure of 10-40Pa to maintain the cabin. However, when producing high biological activity drugs (such as anti-tumor drugs and sex hormone drugs). Negative pressure operation of -40~-10Pa can be used, which not only maintains the sterile state inside the cabin, ensures that the product is not contaminated by microorganisms, but also ensures that the drug does not leak outside the cabin, causing harm to the operators. The air entering and exiting the cabin is filtered through H14 level filters, and there will be no contamination of the interior of the cabin due to pressure loss.
  
4. The sterile isolator of the hard cabin is integrated with a vaporized hydrogen peroxide generator, achieving integrated control of the isolator host PLC, automatic sterilization, and automatic pressure maintenance operation.
  
5. Built in cleaning water and compressed air spray gun interfaces are used for cabin cleaning. Multi functional real-time monitoring interfaces and verification interfaces are reserved for real-time wind speed, dust particle monitoring, and floating bacteria detection verification work.
  
6. All units adopt modular design, which can be configured and specified according to customer process needs. For example, air lock chambers or RTP systems (laminar flow with hydrogen peroxide sterilization) can be installed on one or both sides, or multiple isolators can be connected according to process requirements, and pressure gradients can be set between them to achieve different operational functions.
  
7. Complies with the relevant requirements of the 2010 version of GMP for isolators.
  
Hangzhou Qikun Technology Co., Ltd. is a comprehensive high-tech enterprise specializing in the research and development, design, manufacturing, sales, and service of water analysis instruments, water analysis sensors, and sterile isolation systems. It is currently one of the largest professional manufacturers of electrochemical analysis instruments and sensors in China.
  
Hangzhou Qikun Technology Co., Ltd.'s products are now widely used in biopharmaceuticals, petrochemicals, power plants, food factories, research institutes, environmental water treatment monitoring. They are inspection equipment for food factories, enterprise discharge treatment, drinking water plants, waterworks, domestic sewage treatment, surface water, rivers, lakes, and ocean micro measurement.