Problem 1: Whitening, cracking, or swelling of the bottle body

This is a typical manifestation of incompatibility between solvents and bottle materials. Commonly used to contain strong polar solvents (such as tetrahydrofuran, dichloromethane, DMF) in polypropylene (PP) or polyethylene (PE) bottles. It should be stopped immediately and replaced with glass bottles or fluorinated polymer bottles (such as PFA, FEP), which have good tolerance to the vast majority of organic solvents and strong acids and bases. Before use, it is necessary to consult the solvent compatibility table to avoid the wrong choice of "replacing glass with plastic".

Problem 2: The bottle cap is not tightly sealed, resulting in leakage or evaporation

Due to improper or aging material of the bottle cap gasket (spacer). Standard silicone/PTFE gaskets are suitable for most solvents, but they are prone to swelling and failure in non-polar solvents such as hexane and toluene. Full PTFE gaskets or Kel-F gaskets should be selected to enhance solvent resistance. At the same time, check if the bottle cap is tightened, but avoid excessive force that may cause thread slippage or deformation of the spacer. For long-term storage, a screw cap with a central hole cover can be used to enhance the sealing level.

Problem 3: Label blurring, detachment, or solvent penetration

Ordinary paper labels are prone to damage in organic solvent environments. Chemical resistant label materials such as polyester (PET), polypropylene (PP), or Teflon labels should be selected and printed with solvent resistant ink. After pasting, it can be covered with a transparent protective film or labeled with a cover. A better solution is to use direct engraving or laser marking technology to mark the bottle body and achieve identification.

Question 4: Damaged or slippery threads on the bottle mouth

Frequent opening and closing or improper use of tools (such as excessive tightening of wrenches) can easily cause damage to the threads of plastic bottles. The bottle cap should be manually tightened to seal, avoiding the use of metal tools. Choosing a bottle body or glass bottle with reinforced design can enhance durability. For automated sampling systems, ensure that the robotic arm has moderate force.

Question 5: Bottle contamination or cross contamination

When reusing solvent resistant bottles, if not cleaned properly, residues can contaminate the new sample. It is strongly recommended to use high-purity solvent bottles once. If it needs to be reused, it must go through a strict cleaning process: first rinse with compatible solvents, then rinse with deionized water, and dry in a clean oven. Avoid using ultrasonic cleaning to prevent stress cracking of the bottle body.