The following is a detailed technical explanation about the installation of drug cabinets, covering the key points of the entire process from preliminary preparation to final acceptance:
1、 Preparation work before installation
1. Site investigation and suitability assessment
-Confirm that the installation area meets the requirements of GB 50346-2018 Building Technical Code for Biosafety Laboratories, with a ground flatness error of ≤ 3mm/m and a bearing capacity of ≥ 800kg/㎡ (for heavy-duty drug cabinets).
-Verify environmental parameters: Control relative humidity within the range of 45% -65% RH, temperature fluctuation within ± 2 ℃, and stay away from strong electromagnetic interference sources (such as large motor equipment).
-Reserve no less than 80cm of operating channels and emergency evacuation space, in compliance with NFPA 101 life safety regulations.
2. Infrastructure supporting construction
-The power supply needs to be equipped with an independent circuit with a voltage stability of ± 5%. It is recommended to install UPS uninterruptible power supply to ensure continuous power supply for key control systems.
-The water supply and drainage system is equipped with a pre filter, with a water pressure range of 0.2-0.4MPa, a drainage pipe diameter of not less than DN50, and a slope of 3%.
-Special drug cabinets (such as low-temperature storage type) need to be pre embedded with cold chain pipelines in advance, using a double-layer vacuum insulation structure, and the refrigerant filling amount should be executed according to the nameplate markings.
3. Equipment unboxing inspection procedure
-According to the packing list, check the integrity of the host, accessories, and random files item by item, with a focus on checking whether the glass door body is damaged (the light transmittance should be ≥ 92%), and whether the metal frame coating is uniform without peeling off.
-Use an infrared thermal imager to detect the initial state of the refrigeration system. The temperature difference on the evaporator surface should be ≤ 2 ℃, and the operating current of the compressor should not exceed 110% of the rated value.
-Establish equipment files, record serial numbers, production batch numbers, and initial startup parameter benchmark values.
2、 Installation process of main structure
1. Basic positioning and leveling
-Using a laser level for three-dimensional positioning, the horizontal deviation is controlled within ± 1mm, and the vertical tolerance is ≤ 1.5mm/m.
-The tightening torque of the anchor bolt shall reach the 12th strength grade specified in ISO 898-2 standard, and the depth of screwing shall not be less than 1.5 times the diameter of the bolt.
-The curing period of concrete foundation shall not be less than 7 days, and subsequent operations can only be carried out after the compressive strength reaches 75% of the design value.
2. Modular component assembly
-The connection between the side panel and the top cover is double fixed with self tapping screws and structural adhesive, with a screw spacing of ≤ 300mm and a glue seam width of 8-10mm.
-When installing laminated support bars, pay attention to distinguishing the front and rear directions. The road surface with anti slip patterns should face outward, and the deflection deformation of each layer after loading should not exceed 1/300 of the span.
-Preheat the door seal to 50 ℃ and soften it before pasting. Leave 2mm expansion allowance at the interface, and use a special pressure roller to compact and eliminate bubbles.
3. Electrical system integration
-The cross-sectional area of the main power line is not less than 6mm ² copper core cable, the grounding resistance is less than 4 Ω, and the operating current of the leakage protector is ≤ 30mA.
-The power density of the LED lighting system is ≤ 8W/m ³, the illuminance uniformity is>85%, and the color rendering index Ra is ≥ 90.
-The calibration of the temperature and humidity controller follows the JJF 1302-2011 standard, with a set point error of ± 0.5 ℃ and a hysteresis of ≤ 0.3 ℃.
3、 Special function debugging
1. Verification of temperature control system
-Set the target temperature under no-load condition, and monitor continuously for 4 hours after stabilization. The temperature fluctuation range should be within ± 1 ℃ of the set value.
-The full load test uses standard calibration weights to simulate the maximum load, and the cooling rate should meet the technical specification of not exceeding 90 minutes from room temperature to the set temperature.
-The threshold for over temperature alarm is set to an upper limit of+2 ℃, with a delay response time of less than 10 seconds and an audible and visual alarm intensity of ≥ 85dB (A).
2. Safety protection interlock test
-After the emergency stop button is triggered, all moving parts should stop running within 2 seconds, and the operating force of the emergency door opening device should be ≤ 50N.
-When the ultraviolet disinfection lamp is working, it will automatically turn off when personnel approach the sensing area, and the radiation intensity will decay below the safety limit for less than 1 second.
-The sensitivity of the gas leak alarm system is calibrated to 25% LEL of the lower explosive limit, with a response time of<30 seconds and a linked exhaust fan ventilation rate of ≥ 12 times/hour.
4、 Completion acceptance and delivery
1. Performance parameter retest
-Re measure key indicators using certified instruments: temperature uniformity ± 1.5 ℃, humidity control accuracy ± 3% RH.
-The noise level test should not exceed 65dB (A) at a distance of 1 meter from the front of the equipment, and the vibration amplitude should be less than 0.5mm/s.
-The insulation resistance test shows that both the phase to phase and ground resistance are greater than 2M Ω, and there is no breakdown phenomenon during the withstand voltage test at 1500V/min.
2. Document handover and training
-Provide complete completion drawings, operation manuals, and maintenance procedures, including a list of vulnerable parts and recommended replacement cycles.
-Organize on-site practical training, covering daily inspection points, common troubleshooting, and emergency plan drills, with a pass rate of 100% in the assessment.
-Sign a quality assurance agreement, specifying the warranty period for the entire machine (usually 12 months) and extending the warranty for key components to 36 months.
By strictly following the standardized installation process mentioned above, it is possible to ensure that the drug cabinet reaches its optimal operating state, meets GSP certification requirements, and lays a solid foundation for subsequent standardized management.