Implementation and Application of Ultrasonic Extraction Technology for Traditional Chinese Medicine

Abstract:China is the birthplace of traditional Chinese medicine and holds a significant position in the resources of Chinese herbal medicine.To improve the therapeutic effect of traditional Chinese medicine, its effective ingredients must be fully extracted. ultrasonic waveExtraction, also known as ultrasonic assisted extraction or ultrasonic extraction, is mainly used for extracting traditional Chinese medicine through ultrasonic wavesAccording to the existence state, polarity, solubility, etc. of the active ingredients in the substance, they quickly react under ultrasoundQuickly enter the solvent to obtain a mixed extract of more components, then separate, refine, and purify the extract using appropriate methods, and finally obtain the desired drug material. In recent years, the application of ultrasound technology in the extraction of Chinese herbal medicine has become increasingly widespread, and has achieved remarkable results in the extraction of Chinese herbal medicineSignificant achievements have been made.

1. Project Introduction

The components contained in Chinese herbal medicine are relatively complex, and due to the different methods of decoction for different types of Chinese herbal medicine,Relying on traditional Chinese medicine extraction and separation methods, there are generally low extraction rates of effective ingredients and impuritiesWith the modernization of traditional Chinese medicine, there are disadvantages such as low clearance rate, high energy consumption, and long production cycle”The process'sAccelerate the application of ultrasound technology in various large and small traditional Chinese medicine enterprises. to improveThe extraction rate of Chinese herbal ingredients was selected by a pharmaceutical company in Henan ProvinceThe ultrasonic extraction equipment produced can operate at high temperatures100Extract according to traditional Chinese medicine at ℃It has been working continuously for a long time and has had a good effect on the extraction of most Chinese herbal ingredientsFruit.This device combines the extraction method of traditional Chinese medicine and decocts and extracts water-soluble Chinese medicine by adding drinking water

Used in the process of sexual ingredients, the liquid is filtered through a filtering device to obtain a medicinal solution. The medicinal solution can be concentrated in a double effect and then filtered out of a paste after spherical concentration, or filtered out of a clear liquid after alcohol precipitation for a certain period of time after double effect concentration. The clear liquid can be recovered from alcohol and filtered out of a paste, or filtered out of a paste after spherical vacuum concentration after water precipitationCream. In actual production, the operation steps of ultrasonic equipment are as follows:

1） After the boiling of the boiling boiler, turn on the main power switch of the ultrasonic equipment and turn on the deviceAutomatically search for the resonant frequency of the ultrasonic transducer under operating conditions, and run it throughThe resonant frequency of the ultrasonic transducer under automatic tracking conditions during the process;

2） Turn off the main power of the ultrasonic equipment before boiling and filtering, or before passing through the steam directlyClosed;

2. Project operation

The project was officially put into operation in the extraction workshop of a traditional Chinese medicine pharmaceutical company in Henan Province in August 2013, and everything is running normally now. It is a physical process for extracting Chinese herbal medicine, and no chemical reactions occur throughout the entire extraction process, which does not affect the physiological activity of most active ingredients in drugs. Avoiding the adverse effects of traditional Chinese medicine decoction and reflux methods with prolonged heating on active ingredients, improving the extraction rate of active ingredients, saving raw materials, and promoting the full utilization of Chinese medicine resources, thus improving economic benefits.

3. Effect feedback

After several months of data analysis, good results have been achieved in the extraction of various drugs such as Liuwei Dihuang Wan, Guipi Wan, Tianwang Wan, etc. The extraction rate of most Chinese medicinal materials has increased by 5% -15%. After testing by various process departments of the company, it does not affect the active ingredients of most drugs.

It has been working continuously for a long time and has had a good effect on the extraction of most Chinese herbal ingredientsFruit.