In daily laboratory work, manual pipetting, dispensing, and volume control are not only time-consuming and labor-intensive, but also prone to data bias caused by human operational errors, and face potential risks such as dangerous sample contact and cross contamination.AutoTip - ∞As the core equipment for laboratory automation upgrade, the liquid processing workstation integrates full functions such as robotic arm grasping, precise liquid transfer, intelligent liquid dispensing, and automatic volume control, reconstructing the liquid processing process with "unmanned operation+high-precision output". This article will delve into its working mechanism and reveal how it achieves efficient operation throughout the entire process from sample capture to data archiving.

1、 Core Work Logic: Building One stop automated closed-loop system

The core advantage of the Aobo intelligent liquid processing workstation lies in breaking through the limitations of a single function and forming The complete closed-loop of "sample loading → automatic processing → data recording → compliance output". Its working logic revolves around the three core principles of "replacing manual labor, precision and controllability, and safety and efficiency". Through modular integration and intelligent algorithm collaboration, it achieves full range liquid processing requirements from 1 μ L trace to 50000 μ L constant, without the need for manual intervention to complete complex experimental processes.

The entire workflow can be simplified as follows: sample recognition → robotic arm grasping and transportation → automatic capping/twisting → precise liquid transfer/dispensing/volume control → pollution prevention and control → data synchronization → sample archiving. Each link is seamlessly connected, avoiding the uncertainty of manual operation and greatly improving experimental efficiency.

2、 Disassembling the working principle of key modules: precise and efficient core support

1. Robot arm grasping system: laboratory“Intelligent robotic arm”

As the "core execution unit" of the workstation, the collaborative six axis robotic arm is the key to achieving automated grasping and transportation, and its working accuracy directly determines the overall process stability:

High precision positioning: Equipped with positioning algorithms, the positioning accuracy can reach ± 0.02mm, and it can accurately identify containers of different specifications, even in densely arranged sample racks;

Intelligent recognition and protection: Combined with deep learning technology, automatically identify the status of sample bottles, and immediately alert and pause in case of abnormal situations; Equipped with anti-collision detection and replaceable end fixtures with anti drop design to avoid sample damage and equipment failure;

Flexible transfer scheduling: Supports multi-directional motion trajectory planning, enabling efficient transfer of samples between the capping module, pipetting station, and tray area. Combined with automatic tray function, it achieves orderly sorting of samples and adapts to subsequent experimental processes.

2. pipetting/solution preparation/Fixed volume core module: precision“Where the soul is located”

This module is the core functional unit of the workstation, integrating sampling technology and intelligent liquid control algorithms to achieve precise implementation of the three core functions:

Full range precise pipetting: supports single channel or multi-channel configuration, with a minimum spacing between channels of only9mmAdaptation from1μLMicro transfer to50000μLVarious scenarios of constant pipetting; Equipped with liquid level automatic tracking technology, it can sense the liquid level height in real time, avoid suction or residue, and ensure the accuracy and repeatability of liquid transfer;

Intelligent liquid dispensing and volume control: Built in multiple predefined liquid parameters, supporting precise multi-component ratio and automatic volume control；

Abnormal detection and warning: Real time monitoring of liquid status during the pipetting process. Once an abnormality is detected, the operation is immediately suspended and an alarm is issued,

Ensure the reliability of experimental data.

3. Auxiliary function module: smooth operation throughout the entire process“Guarantee line”

Automatic capping/screwing module: It can automatically unscrew and tighten covered containers without manual intervention, saving manpower and avoiding sample contamination or container damage caused by manual capping. It is suitable for various types of capped consumables;

Eliminate cross contamination of samples; Simultaneously adopting tip head and closed pipeline design to cut off the pollution path from the source;

Modular expansion unit: supports customized integration of barcode scanning and other functional modules, which can be flexibly combined according to experimental needs to achieve a "one-stop" liquid processing solution. It is compatible with standard carriers such as test tubes, deep hole plates, PCR consumables, and also supports non-standard customization.

4. Intelligent Control and Data Management System: Operations and Compliance“Central brain”

The intelligent operation and data traceability capability of the workstation rely on an integrated control system at its core

Convenient operation interface: equipped with touch screen and Windows visual operation interface, with clear operation logic, even beginners can quickly get started; Support drag and drop process editing, import experimental parameters into Excel spreadsheets to automatically generate operation scripts, without the need for professional programming knowledge;

Real time monitoring and warning: During the experimental process, the running status is displayed in real time, including the progress of liquid transfer, liquid volume statistics, etc. Key data is presented intuitively, and abnormal situations are automatically alarmed;

Data compliance and integration: The open interface seamlessly integrates with laboratory management software (LIMS), automatically stores and archives operation logs and experimental data, and supports traceability queries,satisfy GLP/CNAS and other compliance certification requirements ensure worry free laboratory audits.

3、 Why can it be achieved Accurate, efficient, and safe? Three major technological highlights

Multi technology collaborative precision control: The precise positioning of the six axis robotic arm and the automatic liquid level tracking detection system work together to control errors from the entire process of "positioning suction discharge", ensuring high repeatability in liquid transfer, dispensing, and volume control;

Full process closed-loop risk prevention: multipledirectionTo avoid the risks of personnel contact and sample contamination, and meet the requirements of biosafety;

Modular design enhances flexibility: The core functional modules and expansion modules can be freely combined to meet the standardization needs of different industries such as drug development, clinical diagnosis, and environmental monitoring, as well as to support customized non-standard processes. One device can replace multiple traditional instruments, saving laboratory space.

4、 Multi industry adaptation: covering all scenarios with automated liquid processing

The working mechanism design of the Aobo intelligent liquid processing workstation fully considers the experimental needs of different industries and achieves full scene adaptation:

Drug development and production: supporting high-throughput screening, batch pipetting and dispensing in vaccine development, accelerating the process of new drug launch;

Genomics and Cell Biology: Adaptation to Nucleic Acid ExtractionPCRSystem construction, protein sample processing, and other scenarios ensure the activity and experimental accuracy of sensitive samples;

Clinical diagnosis and third-party testing: meet the batch sample processing needs in serological testing, food and drug testing, and environmental monitoring, and improve testing efficiency and data reliability;

Industrial and Special Applications: Suitable for special liquid handling in the microelectronics industry, cosmetics research and development, and judicial appraisal, able to withstand some corrosive liquids and achieve safe and efficient operation.

5、 Summary: Redefining Laboratory Liquid Handling Standards

Aobo Intelligent Liquid Processing Workstation The working mechanism of "precise grasping of robotic arm+precise processing of core module+full process control of intelligent system",Say goodbye to the tedious and error of manual operation, and achieve full process automation of functions such as pipetting, dispensing, and constant volume. It's not just a machineLiquid processing equipment is the core support for the digital and intelligent upgrading of laboratories - it not only liberates the hands of laboratory personnel, allowing scientific research to focus on core research and development, but also provides reliable guarantees for experimental results through data traceability and compliant operation.

With full range coverage from 1 μ L to 50000 μ L, and flexible adaptation from standard processes to customized requirements, Aobo Intelligence is reconstructing laboratory liquid processing logic with hardcore technology, becoming the preferred solution for cost reduction, efficiency improvement, quality improvement, and compliance in various industries' laboratories.