Spray drying is a method of systematic technology applied to material drying. After liquid materials are atomized in the drying chamber, in contact with hot air, moisture vaporizes instantaneously to obtain dried products. This method can directly dry solutions and emulsions into powder or granular products, eliminating processes such as evaporation and crushing, and the particles obtained are evenly distributed.
Spray drying has the characteristics of fast heat transfer, rapid water evaporation, instant drying time, good product quality and solubility, which can improve the dissolution rate of some preparations. In addition, spray drying can also be used to prepare microcapsules.
"If you want to do a good job, you must first use your tools". According to the physical or chemical properties of different materials, as well as the size and solubility of the powder or particle required for experiments, researchers may need a different type of laboratory spray dryer to obtainzui理xiangThe experimental effect.
Firstly, materials with high sugar content (such as juice, herbal extracts, or natural product extracts) or heat sensitivity
Because most polysaccharide disaccharides have a low melting point, the sugar melts when heated, and the polysaccharide disaccharides themselves are easy to absorb moisture, so ordinary spray dryers are prone to stick to the wall, and it is not easy to get good dry powder or particles.
In addition, such as enzyme preparations, live bacteria and some macromolecular materials that are easy to denature under high temperature, materials are very easy to inactivate or denature when using ordinary spray dryers. At this time, better experimental results can be obtained by reducing the inlet air temperature and outlet air temperature of spray dryers. Vacuum laboratory spray dryers can test at a lower inlet air temperature. For example, the inlet air temperature of laboratory spray dryers can be set at 30 ℃~300 ℃. Generally, materials with high sugar content can get better particles. The sugar content of some materials may have a lower melting point. At the inlet air temperature of 60-80 ℃, the spray dryer process can be completed, such as enzyme preparations, live bacteria, etc., which can be dried instantaneously at such a low temperatureWan QuanNot affected.
Secondly, the solvent is organic solvent or easily oxidizable material
It is difficult to dry materials containing organic solvents during spray drying. Generally, organic solvents are flammable and explosive. Explosion proof closed laboratory spray dryer enables materials to circulate in a closed drying system. The whole system is filled with inert gas (such as nitrogen or argon), which can avoid the contact between organic solvent gas and external oxygen air, ensuring safe production. The experimental organic solvent spray dryer adopts a safe nitrogen (or other inert gas) closed circulation mode. The whole system is fully closed, and the oxygen concentration is monitored online. Once the oxygen concentration in the system reaches 1.5%, the system will automatically shut down and give an alarm. It is a small spray dryer dedicated to organic solvent in the laboratory with good safety and easy operation. The system uses the nitrogen closed circulation mode and adopts solventsWan QuanThe combination of recycling methods can be used to treat solvents with flammability and toxicity, and to dry easily oxidizable substances. Moreover, due to the low boiling point of organic solvents, low-temperature drying can be used to dry substances that are prone to thermal denaturation.
Thirdly, materials with extremely poor thermal sensitivity or requiring improved solubility
Some materials cannot be heated at all, and traditional freeze-drying takes a very long time. Moreover, the dried materials are blocky, have poor flowability, and poor solubility.
Compared with traditional freeze drying technology, GG-6000Y laboratory spray freeze dryer has the following advantages:
01. The atomized and dispersed small liquid droplets quickly freeze when immersed in low temperature, which can weaken the growth of ice crystals, reduce the damage of ice crystals to liposomes, and avoid drug leakage and burst release.
02. Frozen samples are dried in vacuum to form spherical particles with microporous structure, which have good fluidity, and the particle size can be adjusted by changing the spray process. GG-6000Y laboratory spray freeze dryer is suitable for low-temperature drying of heat sensitive, viscous, active materials and materials with high sugar content, such as natural product extracts of Chinese herbal medicine, dairy products, biological agents, enzyme preparations, fruit juice, polymer materials, etc.
For materials that need to directly obtain nanomaterials, the laboratory spray freeze dryer is also aJi is goodThe choice.
Fourth, conventional materials
Some laboratories are used for the preparation of conventional powders or drying of materials. The high-temperature laboratory spray dryer can be selected, which is small in size, fast in speed, low in noise, and easy to operate. Moreover, 20ML of materials can be used to complete an experiment. The dried powder has good sphericity, and the particle size is too distributed. In particular, the machine is equipped with spray head water cooling device and tower wall purging function, which greatly expands the application of the laboratory spray dryer.