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Detailed introduction of capillary column
Date: 2025-03-06Read: 1

capillary columnIt is a key component of capillary chromatography. It has the advantages of being relatively large, having high specific permeability, fast analysis speed, and high total column efficiency. It can solve problems that cannot be solved by filling columns.

Features:

1. Good column permeability, low impedance, and can be used with long chromatography columns.

2. The total column efficiency is high, greatly improving the separation ability for complex mixtures.

3. The column capacity is low, allowing for a small injection volume.

The capillary column is usually made of fused silica glass, which has flexibility and high temperature resistance. The inner diameter is extremely thin (0.1-0.5 mm), the length is long (10-100 meters), and it is coiled in a spiral shape to adapt to the instrument. Coat the inner wall with a very thin layer of fixed phase (such as polymer or chemically modified layer) for separating compounds.

Application fields:

Environmental monitoring: detecting trace pollutants in the atmosphere and water.

Food safety: analysis of pesticide residues and additives.

Petrochemical industry: separation of hydrocarbon compounds.

Pharmaceutical: drug purity testing, metabolite analysis.

capillary columnCan be installed on gas chromatographs equipped with dedicated capillary column connection devices. For capillary columns with larger inner diameters, their installation and connection are relatively simple and can be used in conjunction with special injection port devices. However, capillary columns with smaller inner diameters require specialized connection devices and injectors. Regular maintenance and upkeep are required during use, including cleaning, aging, and other treatments.