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What are the applicable scope of X-ray live animal imaging system?
Date: 2025-11-10Read: 0
The scope of application of the X-ray live animal imaging system focuses on research scenarios such as structural observation, disease monitoring, and efficacy evaluation of small animals (mice, rats, etc.) in their live state, covering multiple fields such as basic medicine, pharmacy, and life sciences, as follows:

1、 Basic Anatomy and Developmental Biology Research

  • Observation of skeletal system: Clear display of small animal skeletal morphology, used for basic research on skeletal development abnormalities, osteoporosis, skeletal deformities, and dynamic tracking of embryonic bone formation.
  • Organ structure localization: Observe the contours and positions of organs such as the liver, kidneys, heart, and lungs, and study the changes in organ morphology during normal anatomical structure and development.

2、 Disease model construction and monitoring

  • Tumor research: Dynamically monitoring the growth size, volume changes, infiltration range, and metastasis of tumors in vivo, achieving long-term tracking without sacrificing animals, and providing data for the study of tumor occurrence and development mechanisms.
  • Orthopedic disease research: monitoring the process of fracture healing (such as callus formation, blurred fracture lines, and disappearance progress), the effectiveness of bone defect repair, and the dynamic changes in bone density in osteoporosis models.
  • Cardiovascular disease research: combined with contrast agents, it can display the morphology of blood vessels and be used for in vivo monitoring of atherosclerotic plaque formation, vascular stenosis, thrombosis and other models.
  • Organ lesion research: Observe abnormal changes in organ morphology in disease models such as hepatitis, nephritis, and pulmonary fibrosis, and evaluate the degree of lesion progression.

3、 Efficacy evaluation of drugs and medical devices

  • Evaluation of anti-tumor drugs: Long term monitoring of changes in tumor volume after administration, quantitative evaluation of the inhibitory effect and onset time of drugs on tumors.
  • Evaluation of bone repair drugs/materials: Evaluate the improvement effect of osteoporosis treatment drugs on bone density, or the fusion status and degradation of implant materials such as artificial bone and bone cement in vivo.
  • Cardiovascular drug evaluation: Observe the improvement effect of drugs on vascular stenosis and thrombosis, as well as their impact on cardiac morphology and function.
  • Medical device implantation evaluation: Monitor the positional stability, biocompatibility, and surrounding tissue reactions of implanted devices such as vascular stents, artificial joints, and orthopedic screws in the body.

4、 Other special research scenarios

  • Gene editing animal model validation: Observe whether the bones, organs, and other structures of small animals (such as gene knockout mice) exhibit expected anatomical abnormalities after gene editing.
  • Trauma model research: After establishing burn, trauma and other models, monitor the changes in morphological structure during tissue repair in vivo.
  • Infectious diseases research: combined with angiography or specific markers, observe the range of infection sites (such as bacterial and viral infection foci) and the regression after treatment.