The animals and plants commonly used in experiments are as follows:
Common experimental animals
mouse
Usage: Widely used in disease models (such as tumors, immune deficiencies), genetic research, and drug toxicity testing.
Advantages: Small size, fast reproduction, clear genetic background, suitable for large-scale experiments.
Case: Transgenic mice are used to simulate human genetic diseases, such as Alzheimer's disease models.
rat
Purpose: Cancer research, toxicology experiments, and behavioral research.
Advantages: Moderate size, convenient for surgical operation and long-term observation.
Case: Inducing a rat liver cancer model and studying the mechanism of action of carcinogens.
rabbit
Usage: Ophthalmic stimulation testing (such as cosmetic safety assessment), orthopedic research (such as joint injury repair).
Advantages: Large eyeballs, bone structure similar to humans.
Case: The Dreze test (eye irritation test) was widely used on albino rabbits and is gradually being replaced.
dog
Purpose: Research in cardiology, endocrinology, and osteoarthritis.
Advantages: High similarity to human physiology, suitable for complex disease models.
Case: Study the dog model of diabetes and develop insulin treatment scheme.
Monkeys (rhesus monkeys, macaques)
Purpose: Neuroscience, neurology research, and vaccine development.
Advantages: Highly homologous to human genes, with complex behavior.
Case: Rhesus monkeys are used in AIDS vaccine research to simulate human immune response.
Frog (African clawed frog)
Purpose: Developmental biology, DNA research, and embryology.
Advantages: Eggs and embryos are transparent, making it easy to observe the development process.
Case: The African clawed frog was the first vertebrate to be successfully cloned.
naked mole rat
Purpose: Research on anti-cancer and exploration of aging mechanisms.
Advantages: Almost no cancer, long lifespan (up to 30 years), strong hypoxia tolerance.
Case: Study its cellular mechanism and search for human anti-cancer therapies.
Commonly used plants in experiments
pea
Purpose: Classic experiments in genetics (such as Mendelian laws of inheritance).
Advantages: Self pollination, significant differences in traits, easy to statistically analyze.
Case: Mendel proposed the law of gene segregation and free combination through pea hybridization experiments.
Arabidopsis thaliana
Purpose: Plant molecular biology, gene function research.
Advantages: Small genome size, short lifespan (about 6 weeks), and easy genetic transformation.
Case study: Investigating the flowering time gene of Arabidopsis thaliana and revealing the mechanism of plant photoperiod regulation.
corn
Purpose: Genetic and cytological research (such as chromosomal variations).
Advantages: Large chromosome size and small number (10 pairs), easy for microscopic observation.
Case: McClintock discovered "jumping genes" (transposons) through corn research.
tobacco
Purpose: Plant virology, gene editing technology validation.
Advantages: Easy to infect viruses, strong regenerative ability, suitable for transient expression experiments.
Case: Tobacco leaves were used to validate the efficiency of CRISPR/Cas9 gene editing.
rice
Purpose: Crop genetic improvement and stress resistance research.
Advantage: The genome of a globally important food crop has been sequenced.
Case study: Investigating salt tolerant genes in rice and cultivating salt tolerant varieties.