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Beijing Dongfang Yuantong Technology Development Co., Ltd

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Standard Operating Procedure for Capintec Activity Meter
Date: 2025-11-27Read: 0


Applicable devices:CRC-55tRTheCRC-25RTheCRC-55tPETWaiting for mainstream models

Core objective: Ensure activity measurement accuracy of ≤±2%Comply with nuclear drug safety regulations

1、 Operation steps

1. System initialization

Before starting up, check the power grounding, turn on the host power, and enter the standby interface after passing the device self-test.

preheat15Minutes (screen display background value fluctuation < ±)0.1MCiWhen considered stable.

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2. Nuclide selection

-pressISOTOPE→ Use the directional keys to select the target nuclide (such as ¹⁸)F⁹⁹ᵐTc⁶⁸Ga)→ PressENTERConfirm.

-Special nuclide: If not pre stored, the half-life needs to be manually entered (pressMANUALinputTHalf value).

3. Background calibration

-Empty load measurement room → Long pressZERO 3Second → Screen Display0.00 MBqIf the background>1MCiEnvironmental radiation needs to be investigated.

4. Sample measurement

step Suddenly:

Inject radioactive liquid into a designated standard test tube (liquid level ≥)3cm).Place the test tube into a lead protection canister (marked with a radioactive label on the canister) and insert it vertically into the center slot of the measurement chamber.-Close the shielding cover → PressMEASKey → Device automatically reads activity (display unit can be switched)MBq/mCi).

Accuracy guarantee: When the measured value continuously fluctuates, record it after the number stabilizes (usually ≤5Seconds).

5. data output

pressPRINTPrint results (automatically record measurement time, nuclide, activity values).

No printer model: Manually record screen data (accurate measurement time needs to be synchronously recorded).

6. Shutdown maintenance

-Take out the sample → Use75%Wipe the inner wall of the probe with an ethanol swab → turn off the power and unplug the plug.

IIQuality Control and Calibration

item eye

frequency rate

mark accurate

Operation method

Background calibration

daily

Reading ≤0.05MCi

Empty load executionZEROcalibration

accuracy verification

monthly

Error ≤±5%

Using ¹³ ⁷CsReference source measurement comparison

Linear detection

quarterly

quarterly

Quarterly measurement of gradient activity source(1-50mCi

annual inspection

every year

comply withNMPAcertification

Implemented by authorized institutions








3、 Key precautions

1. safety protection

Wear double-layer gloves during operation+Lead scarf, the sample must be shielded with a lead canister.

Measure high activity samples (>50mCi)Before proceeding, confirm that the device range supports(CRC-55tRThe upper limit is200mCi).

2. Avoiding errors

Test tube position deviation>2mmMay cause errors ±3%Ensure vertical centering.

Environmental temperature changes>5℃ needs to be preheated again (optimal temperature)20±2℃)。

3. Pollution emergency response

step1Immediately cover the spilled medicine with absorbent paper → Set1Mi Isolation Zone

step2Scan the contaminated area with a radiometer → Use10%Sodium hypochlorite solution for decontamination

step3Place contaminated items in the lead waste bin → Report to the radiation safety administrator


4、 Technical support

Service in China: Background: Dongfang Yuantong Technology


Fault code handling:

Err 05The measurement room door is not tightly closed → Close the shielding cover again

Err 12Background too high → Check environmental radiation or restart calibration

Customized service: providing department exclusive servicesSOPAnd training (equipment model needs to be provided)

Process advantage: Full process operation ≤3Minutes, supportFDA 21 CFR Part 11Compliance data tracking.

Attachment suggestion: Post the "Quick Check List of Operation Points" and emergency contact card next to the equipment to improve disposal efficiency.